METHYLATION ASSAY - AN OVERVIEW

The strategy of HPLC-UV (large overall performance liquid chromatography-ultraviolet), made by Kuo and colleagues in 1980 [seventeen], is still thought to be the current “gold regular” assay for quantifying the amount of deoxycytidine (dC) and methylated cytosines (5 mC) present within genetic genie methylation analysis a hydrolysed DNA sample.